This weekend's CAF Champions League action will be headlined by an encounter between Zamalek and TP Mazembe.
The two former winners will be battling for Group A top spot with DR Congolese giants Mazembe having already qualified for the quarterfinals.
Egyptian football powerhouse, Zamalek will also be looking to avenge the 3-0 defeat they suffered against Mazembe in DRC when he two teams meet in Cairo on Friday.
Zambian champions ZESCO United and Angola side Primeiro de Agosto will both be looking to register their maiden win in Group A when they clash in Ndola on Saturday.
Meanwhile, Tunisian outfit Etoile du Sahel will be needing a point in order to qualify for the knockout phase when face record eight-time winners Al-Ahly in Group B clash in Egypt on Saturday.
Zimbabwean side FC Platinum will be desperate for their first win in Group B when they lock horns with Sudanese giants Al-Hilal in Bulawayo on the same day.
While former Moroccan champions Wydad Casablanca will be looking to secure their spot in the knockout phase with a win over Algerian side USM Alger in a Group C match in Morocco on Friday.
South African champions Sundowns will be keen to ensure that they win Group C with a victory against Angolan giants Petro de Luanda in Angola on Saturday.
Lastly, Tunisian giants Esperance de Tunis and Moroccan football heavyweights Raja Casablanca will be battle for Group D top spot when they meet in Rades on the same day.
DR Congo's AS Vita Club will be hoping to record their first win in Group D when they square off with Algerian giants JS Kabylie in Kinshasa on Saturday.